If you rent that home to others, then make sure that you spend no more than 14 days on the property for personal reasons (days spent on repair, furnishing, management, or upkeep don’t count as personal as long as you spend 4 hours and 1 minute during the day on repair, furnishing, management, or upkeep) so that you can deduct 100% of the expenses of that home.
If you live in the home (i.e., have more than 14 days of personal use of the home), then make sure that you conduct business for your small business in that location. That makes your home and travel to the home an ordinary and necessary business expense which might be deductible.